What is AICAR?
AICAR is an AMP analog studied for its ability to enhance cellular energy metabolism and mimic exercise-induced biochemical effects.
Where to Buy AICAR Online
8 vendors in our directory currently list AICAR. The comparison shows each vendor's third-party testing status, COA availability, editorial and community ratings, and any active coupon — ordered by our directory ranking.
| Vendor | Trust signals | Editorial rating | User reviews | Coupon | Visit vendor |
|---|---|---|---|---|---|
| 4.9Rated 4.9 out of 5 | No user reviews | — | Visit site | |
| 4.8Rated 4.8 out of 5 | No user reviews | — | Visit site | |
| 4.7Rated 4.7 out of 5 | No user reviews | — | Visit site | |
| 4.5Rated 4.5 out of 5 | No user reviews | — | Visit site | |
| 4.4Rated 4.4 out of 5 | No user reviews | — | Visit site | |
| 3.6Rated 3.6 out of 5 | No user reviews | — | Visit site | |
| Not yet rated | No user reviews | — | Visit site | |
| Not yet rated | No user reviews | — | Visit site |
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Mechanism of Action
It activates AMP-activated protein kinase (AMPK), increasing glucose uptake, fatty acid oxidation, and mitochondrial biogenesis.
Clinical Research
Cited studies
Researched Benefits
Research on AICAR has focused on the following areas:
- Activates AMPK to support metabolic regulation in research models
- May enhance glucose uptake and insulin sensitivity in skeletal muscle
- Investigated for promoting fatty acid oxidation and reducing adiposity
Side Effects & Safety
Adverse reactions and limitations documented for AICAR include:
- Nausea
- Headaches
